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The Spine

The team is the asset. This is how it distils expertise. From research into software, from teams into agents.

A lumbar vertebra

01Published science

Advancing the field

Everything here rests on work we published, peer-reviewed, in the field's own journals.

Segmentation. A raw CT scan becomes every vertebra, labelled and separated — a deep-learning method that beat every other at the spine segmentation challenge.

Korez, Ibragimov, Likar, Pernuš, Vrtovec. A framework for automated spine and vertebrae interpolation-based detection and model-based segmentation. IEEE TMI, 36(7), 2017.

Yao, Burns, … Vrtovec, … Li. A multi-center milestone study of clinical vertebral CT segmentation. Computerized Medical Imaging and Graphics, 49, 2016.

Korez, Likar, Pernuš, Vrtovec. Segmentation of pathological spines in CT images using a two-way CNN and a collision-based model. MSKI 2017 (LNCS 10734).

Pedicle-screw planning. Every screw's size and trajectory, computed — and proven against real surgical outcomes.

Knez, Likar, Pernuš, Vrtovec. Computer-assisted screw size and insertion trajectory planning for pedicle screw placement surgery. IEEE TMI, 35(6), 2016.

Knez, Mohar, Cirman, Likar, Pernuš, Vrtovec. Variability analysis of manual and computer-assisted preoperative thoracic pedicle screw placement planning. Spine, 43(21), 2018.

Knez, Nahle, Vrtovec, Parent, Kadoury. Computer-assisted pedicle screw trajectory planning using CT-inferred bone density. Medical Physics, 46(8), 2019.

02Clinical software

Guiding the surgeon's hand

We built these methods, by hand, into software surgeons use — FDA-cleared, in the operating room.

Automated spine segmentation

Scan → model

Automated spine segmentation

Every vertebra, labelled and separated.

Editing the spine by hand

Refine

Editing the spine by hand

Brush, HU-brush, lasso — correct or build a segmentation, live.

Automated pedicle-screw planning

Plan the hardware

Automated pedicle-screw planning

Entry point, medial angle, diameter, trajectory — per vertebra.

Deformity-correction planning

Plan the correction

Deformity-correction planning

Aligning the spine level by level — coronal and sagittal, measured.

Our core runs inside FDA-cleared systems shipping today. We build it; our partners put their name on it.

03The product

Moving into the browser

The whole pipeline, in a browser tab. Served, opened, run — no install.

Spine-surgery planning, in the browser

The product

Spine-surgery planning, in the browser

Served from the server, opened in a browser tab — segment, place pedicle screws, measure the correction.

04Agent-native

Letting the agent operate

The app is an interpreter of a language the agent speaks — so the agent builds the tools itself. We hand it a vertebra, its atlas, and one sentence. It fits the atlas, frames every vertebra, measures the curve, corrects it, and packages the whole thing into a reusable tool. What took us years by hand, an agent did in seven minutes.

An agent aligns a spine — and builds the tool that does it

Agent-native software

An agent aligns a spine — and builds the tool that does it

Inspect → fit the atlas → frame every vertebra → measure the curve → correct it → a reusable five-step workflow.

Where this goes

One field. Every field.

We distil expertise into software, into the teams we hand it to, and now into agents. Every field runs the same loop.